We stayed in one of the "Western cabins" which are nearly identical to those in Canyon lodge. The are quiet enough but some weather stripping at the bottom of the door was either chewed or damaged and just after we closed the door it had no trouble running under the door. Another person also told me of similar experiences in one of the new lodges there.
I put a face rag soaked with soap and water and crammed it into the hole when we closed the door. None of the mice we saw the next day were foaming at the mouth.

Don't let the lodge fool you with it's good looks , the cabins are awful. I must say this , It inspired us to spent EVERY waking out out in the park... literally.
To get 3 nights together at one lodge during our stay I had to pick Lake Lodge cabins and got a small cabin at (after taxes) $90 per night. Upon checking in (latest checking I've ever seen) 4:30 pm... I was shocked at the cabins condition...honestly I thought about sleeping in the truck... about an 8x8 room with double bed , plywood walls that hadn't seen fresh paint in 20 yr , ratty /stained worn carpet Non- functioning smoke /carbon dioxide detector a bath the size of one in a small rv, along with a questionable gas heater located inches from the bed and linens. The high security gate latch for a door knob and deadbolt that didn't lock , were the best of the features ....
The best thing Yellowstone could do is bulldoze down these so called guest cabins.