With sunny weather year-round, this upscale Sonoran Desert resort provides immediate access to the towering Santa Catalina Mountains and nearby canyons for hiking, biking, outdoor dining and pool time. Located on more than 150 acres on what was once a cattle ranch, rooms feature feather beds, 20-plus options of pillows, DVD players, cable TV, stereo/CD, mini-refrigerators and in-room coffee and tea service. There is complimentary Wi-Fi. Rooms feature one king or two queen-sized beds. Luxury suites are available with one, two or three bedrooms, kitchen facilities and a washer/dryer. The free-standing Casa Grande will work for up to six people.

Canyon Ranch has proved especially popular for grandmother-mother-daughter getaways, as long as the kids are 14. There are special teen services, high ropes adventures, tennis and golf. There are four pools, including the indoor pool where classes are held. The L-pool outdoors near the tennis courts also has two shaded underwater HydrWorx treadmills. The staff includes registered dieticians, board-certified physicians, licensed therapists and more. There are special parent-child packages.