It’s hard to miss the Charles Hotel, which overlooks the Charles River from Cambridge’s Harvard Square. With views of Boston, the hotel provides a quiet sanctuary for families. Kids are welcomed upon arrival with Kid’s Kits, while pets are also welcome to join the family vacation. Each floor of the hotel features a “Web Cube’ with complimentary Internet and Skype technology the teens will love, while a library featuring bestsellers from Harvard’s Coop is located in the laundry. Guests receive free access to the neighboring Wellbridge Athletic Club, free in-room Wi-Fi, and access to the hotel’s full-service spa. Families can request cribs with bumpers, blankets and fitted sheets. During the day, families may prefer to dine at the hotel’s casual Henrietta’s Table, and then turn to Rialto in the evening for sophisticated Italian. Rooms and suites are comfortably outfitted with down quilts, Bose Wave radios, and flat-screen TVs.